Evaluation of Indonesian and two types of Japanese honey on the acceleration of cutaneous wound healing: an experimental study in mice

Authors

  • Haryanto Haryanto STIK Muhammadiyah Pontianak, Indonesia https://orcid.org/0000-0002-3711-1885
  • Kanae Mukai Kanazawa University, Japan
  • Nakajima Yukari Kanazawa University, Japan
  • Mayumi Okuwa Kanazawa University, Japan
  • Cau Kim Jiu Khon Kaen University, Thailand
  • Junko Sugama Kanazawa University, Japan
  • Toshio Nakatani Kanazawa University, Japan

DOI:

https://doi.org/10.31101/jhtam.912

Keywords:

indonesian honey, japanese honey, wound healing, hydrocolloid dressing,

Abstract

The purpose of this study is to evaluate and clarify the effect of Indonesian honey, two types of Japanese honey and hydrocolloid dressing on wound healing process. Four groups of male mice were treated to produce two circular full-thickness skin wounds on the dorsum. They were then randomly allocated to receive daily Indonesian honey, Japanese honey (Buckwheat and Acacia honey) or hydrocolloid dressing as a control for treatment application. Macroscopic findings were observed from day 0 to 14 after wounding. Microscopic evaluation was assessed using qualitative analysis. The ratios of wound areas for honey groups on day 3 and 7 were smaller than those of the control group. Wound areas of honey groups gradually decreased to almost the same wound area as the control group on day 14, while the wound area of the control group peaked on day 5 and rapidly decreased until day 14. Microscopic finding that Indonesian honey was different with Japanese honey especially Buckwheat honey.

Author Biographies

Kanae Mukai, Kanazawa University

Department of Clinical Nursing, Graduate School of Medical Sciences

Nakajima Yukari, Kanazawa University

Advanced Health Care Science Research Unit Innovative Integrated Bio-Research Core Institute for Frontier Science Initiative

Mayumi Okuwa, Kanazawa University

Advanced Health Care Science Research Unit Innovative Integrated Bio-Research Core Institute for Frontier Science Initiative

Cau Kim Jiu, Khon Kaen University

Faculty Of Nursing

Junko Sugama, Kanazawa University

Advanced Health Care Science Research Unit Innovative Integrated Bio-Research Core Institute for Frontier Science Initiative

Toshio Nakatani, Kanazawa University

Advanced Health Care Science Research Unit Innovative Integrated Bio-Research Core Institute for Frontier Science Initiative

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Published

2019-11-04

How to Cite

Haryanto, H., Mukai, K., Yukari, N., Okuwa, M., Jiu, C. K., Sugama, J., & Nakatani, T. (2019). Evaluation of Indonesian and two types of Japanese honey on the acceleration of cutaneous wound healing: an experimental study in mice. Journal of Health Technology Assessment in Midwifery, 2(2), 80–88. https://doi.org/10.31101/jhtam.912

Issue

Vol. 2 No. 2 (2019): November

Section

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