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Title:
Survival analysis of COVID-19 patients with comorbidities in Bekasi during 2020-2021
Author:
Siti Rapingah Rapingah(1)
Seni Wati Ruddin(2*)
Shinta Silaswati Silaswati(3) (1) Universitas Islam As-Syafi'iyah Jakarta, Indonesia
(2) Universitas Islam As-Syafiiyah Jakarta, Indonesia
(3) RSUD Kota Bekasi, Indonesia
(*) Corresponding Author
10.31101/jhes.2254|
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Abstract
Coronavirus disease 2019 (COVID-19) is a respiratory infectious disease caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). COVID-19 in patients with comorbidities progresses more rapidly to severity and frequently leads to death. Therefore, the objective of this study is to determine the length of survival and estimation of the Hazard Ratio (HR) of COVID-19 patients with comorbidities. The study design used a retrospective cohort of 3,751 samples and was analyzed using Kaplan Meier and cox regression. The survival function description shows the difference in the mean survival of COVID-19 patients without comorbid and patients with comorbidities of 78 days and 23 days, respectively, with HR of 4.4. In conclusion, comorbid COVID-19 patients possess a lower survival and a higher risk of death.
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DOI: https://doi.org/10.31101/jhes.2254
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Badawi, A., & Ryoo, S. G. (2016). Prevalence of comorbidities in the Middle East respiratory syndrome coronavirus (MERS-CoV): a systematic review and meta-analysis. In International Journal of Infectious Diseases (Vol. 49, pp. 129–133). Elsevier B.V. https://doi.org/10.1016/j.ijid.2016.06.015 Beranda | Satgas Penanganan COVID-19. (n.d.). Retrieved October 27, 2020, from https://covid19.go.id/ Chan, J. F. W., Kok, K. H., Zhu, Z., Chu, H., To, K. K. W., Yuan, S., & Yuen, K. Y. (2020). Genomic characterization of the 2019 novel human-pathogenic coronavirus isolated from a patient with atypical pneumonia after visiting Wuhan. Emerging Microbes and Infections, 9(1), 221–236. https://doi.org/10.1080/22221751.2020.1719902 Diyono, B. K. (2021). Faktor Comorbid Covid-19 di Indonesia Scopyng Review. Jurnal Ilmu Kesehatan, 9(1), 51–59. https://ejurnal.stikespantikosala.ac.id/index.php/jik/article/view/201 Docherty, A. B. et al. (2020). Features of 20 133 UK patients in hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: prospective observational cohort study. BMJ, 369. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7243036/ honghua Liu Xing Bing Xue Za Zhi. (2020). Epidemiology Working Group for NCIP Epidemic Response, Chinese Center for Disease Control and Prevention. [The epidemiological characteristics of an outbreak of 2019 novel coronavirus diseases (COVID-19) in China]. Pubmed, 41(2), 145–151. https://doi.org/10.3760/cma.j.issn.0254-6450.2020.02.003 Longato, E., Fadini, G. P., Sparacino, G., Gubian, L., & Di Camillo, B. (2020). Prediction of Cardiovascular Complications in Diabetes from Pharmacy Administrative Claims. Conference, Melecon. 20th IEEE Mediterranean Electrotechnical, 315–320. https://doi.org/10.1109/MELECON48756.2020.9140600 Mahumud, R. A., Kamara, J. K., & Renzaho, A. M. N. (2020). 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Kesintasan Penyakit Ginjal Kronik yang Menjalani Hemodialisis di Rumah Sakit Abdul Moeloek Lampung Tahun 2017-2018. Media Penelitian Dan Pengembangan Kesehatan, 30(3), 257–264. https://doi.org/10.22435/mpk.v30i3.2507 Murillo-Zamora, E., & HERNANDEZ-SUAREZ, C. M. (2020). Survival in adult inpatients with COVID-19. MedRxiv. Sanyaolu, A., Okorie, C., Marinkovic, A., Patidar, R., Younis, K., Desai, P., Hosein, Z., Padda, I., Mangat, J., & Altaf, M. (2020). Comorbidity and its Impact on Patients with COVID-19. SN Comprehensive Clinical Medicine, 2(8), 1069–1076. https://doi.org/10.1007/s42399-020-00363-4 Sari, N., & Muhani, N. (2020). Analisis Survival Pasien Hemodialisis dengan Hipertensi di Lampung Tahun 2016-2018. Media Penelitian Dan Pengembangan Kesehatan, 30(2), 89–96. https://doi.org/10.22435/mpk.v30i2.2251 Satria, R. M. A., Tutupoho, R. V., & Chalidyanto, D. (2020). Analisis Faktor Risiko Kematian dengan Penyakit Komorbid Covid-19. Jurnal Keperawatan Silampari, 4(1), 48–55. https://doi.org/10.31539/jks.v4i1.1587 Smeltzer, Suzanne C. & Bare, B. G. (2017). Smeltzer & Bare Textbook of Medical Surgical Nursing. Lippincott Williams & Wilkins.M. Farrell (Ed.); 1st ed.). Susilo, A., Rumende, C. M., Pitoyo, C. W., Santoso, W. D., Yulianti, M., Herikurniawan, H., Sinto, R., Singh, G., Nainggolan, L., Nelwan, E. J., Chen, L. K., Widhani, A., Wijaya, E., Wicaksana, B., Maksum, M., Annisa, F., Jasirwan, C. O. M., & Yunihastuti, E. (2020). Coronavirus Disease 2019: Tinjauan Literatur Terkini. Jurnal Penyakit Dalam Indonesia, 7(1), 45. https://doi.org/10.7454/jpdi.v7i1.415 Wang, J. J., Edin, M. L., Zeldin, D. C., Li, C., Wang, D. W., & Chen, C. (2020). Good or bad: Application of RAAS inhibitors in COVID-19 patients with cardiovascular comorbidities. In Pharmacology and Therapeutics (Vol. 215, p. 107628). Elsevier Inc. https://doi.org/10.1016/j.pharmthera.2020.107628 Wenjie Yang and Fuhua Yan. (2019). Patients with RT-PCR-confirmed COVID-19 and. Journal of the American Podiatric Medical Association, 96(3), 1. https://doi.org/10.7547/0960272 World Health Organization. (2020). Situation Report-51 SITUATION IN NUMBERS total and new cases in last 24 hours. Situation Report – 51%0AData as reported by national authorities by 10 AM CET 11 March 2020 H Yang, J., Zheng, Y., Gou, X., Pu, K., Chen, Z., Guo, Q., Ji, R., Wang, H., Wang, Y., & Zhou, Y. (2020). Prevalence of comorbidities and its effects in coronavirus disease 2019 patients: A systematic review and meta-analysis. International Journal of Infectious Diseases, 94, 91–95. https://doi.org/10.1016/j.ijid.2020.03.017 Yang, Q., Zhou, Y., Wang, X., Gao, S., Xiao, Y., Zhang, W., Hu, Y., & Wang, Y. (2020). Effect of hypertension on outcomes of adult inpatients with COVID-19 in Wuhan, China: A propensity score-matching analysis. Respiratory Research, 21(1), 172. https://doi.org/10.1186/s12931-020-01435-8 Yuliana. (2020). WELLNESS AND HEALTHY MAGAZINE Corona virus diseases (Covid. Wellness And Healthy Magazine, 2(1), 187. https://wellness.journalpress.id/wellness
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