Vitamin D intake and stroke incidence in adults

Authors

  • Iis Sulastri Universitas 'Aisyiyah Yogyakarta
  • Dittasari Putriana Universitas 'Aisyiyah Yogyakarta

DOI:

https://doi.org/10.31101/jhes.2471
Abstract views 492 times

Keywords:

vitamin D intake, mature age, strokes

Abstract

Stroke is one of the non-communicable diseases which becomes a global health problem. One of the micronutrient intakes associated with a risk factor for stroke is vitamin D, in which a deficiency of this vitamin is associated with the incidence of ischemic stroke. Therefore, the objective of this study is to determine the relationship between vitamin D intake and the incidence of stroke in adulthood. The method administered is analytic observational with a case-control design and encompasses 40 respondents aged 20-60 years who are members of the Happy Embung community of Yayasan Stroke Indonesia (YASTROKI) DI Yogyakarta. The sampling technique was purposive sampling in the YASTROKI community in Yogyakarta, the measuring instrument employed was the Semi-Quantitative Food Frequency Questionnaire (SQ-FFQ). Data were examined by employing Chi square test with the results that more than one third of the respondents in the case group and the control group possessed less vitamin D intake (40% and 85%). There was a significant association between the intake of vitamin D and the incidence of stroke in adults (p = 0.016). This study concludes that adequate nutritional intake, particularly vitamin D, is one way to reduce the risk of stroke and enhance the quality of life of stroke patients.

References

Barral, M., Rabier, H., Termoz, A., Serrier, H., Colin, C., Haesebaert, J., Derex, L., Nighoghossian, N., Schott, A.-M., Viprey, M., & Group, the S. S. (2021). Patients’ productivity losses and informal care costs related to ischemic stroke: A French population-based study. European Journal of Neurology, 28(2), 548–557. https://doi.org/10.1111/ene.14585

Béjot, Y., Bailly, H., Graber, M., Garnier, L., Laville, A., Dubourget, L., Mielle, N., Chevalier, C., Durier, J., & Giroud, M. (2019). Impact of the Ageing Population on the Burden of Stroke: The Dijon Stroke Registry. Neuroepidemiology, 52(1–2), 78–85. https://doi.org/10.1159/000492820

Boehme, A. K., Esenwa, C., & Elkind, M. S. V. (2017). Stroke Risk Factors, Genetics, and Prevention. Circulation Research, 120(3), 472–495. https://doi.org/10.1161/CIRCRESAHA.116.308398

BPJS Kesehatan. (2021, November 18). Penyakit Katastropik Berbiaya Mahal Tetap dijamin Program JKN-KIS. 104. https://bpjs-kesehatan.go.id/bpjs/dmdocuments/ae3544d7f3382ebb639eba99192b5c76.pdf

Bucki, B., Spitz, E., & Baumann, M. (2019). Emotional and social repercussions of stroke on patient-family caregiver dyads: Analysis of diverging attitudes and profiles of the differing dyads. PLoS ONE, 14(4), e0215425. https://doi.org/10.1371/journal.pone.0215425

Bundy, J. D., Li, C., Stuchlik, P., Bu, X., Kelly, T. N., Mills, K. T., He, H., Chen, J., Whelton, P. K., & He, J. (2017). Systolic Blood Pressure Reduction and Risk of Cardiovascular Disease and Mortality: A Systematic Review and Network Meta-analysis. JAMA Cardiology, 2(7), 775–781. https://doi.org/10.1001/jamacardio.2017.1421

Cervantes, C. E., Gomez-Ulloa, D., Elorriaga, A., García, J. M., Md, F., Tapias, I. C., Gatell-Menchen, S., Sidelnikov, E., & Leciñana, M. A. de. (2018). PCV61—Productivity Loss and Local Indirect Costs Associated with Acute Coronary Syndrome And Stroke In Spain. Value in Health, 21, S102. https://doi.org/10.1016/j.jval.2018.09.608

Chaudhuri, J. R., Mridula, K. R., Alladi, S., Anamika, A., Umamahesh, M., Balaraju, B., Swath, A., & Bandaru, V. S. (2014). Serum 25-Hydroxyvitamin D Deficiency in Ischemic Stroke and Subtypes in Indian Patients. Journal of Stroke, 16(1), 44. https://doi.org/10.5853/jos.2014.16.1.44

Che, B., Shen, S., Zhu, Z., Wang, A., Xu, T., Peng, Y., Li, Q., Ju, Z., Geng, D., Chen, J., He, J., Zhang, Y., & Zhong, C. (2020). Education Level and Longâ€term Mortality, Recurrent Stroke, and Cardiovascular Events in Patients With Ischemic Stroke. Journal of the American Heart Association, 9(16), e016671. https://doi.org/10.1161/JAHA.120.016671

Dong, J., Lau, C. W. ai, Wong, S. L. ing, & Huang, Y. (2014). Cardiovascular benefits of vitamin D. Sheng Li Xue Bao : [Acta Physiologica Sinica], 66(1), 30–36. https://doi.org/10.13294/j.aps.2014.0005

Fahmy, E., Sharaf, S., Helmy, H., & Sherif, S. (2019). Vitamin D status in acute ischemic stroke: Relation to initial severity and short-term outcome. The Egyptian Journal of Neurology, Psychiatry and Neurosurgery, 55(1), 18. https://doi.org/10.1186/s41983-019-0068-9

Fattore, G., Torbica, A., Susi, A., Giovanni, A., Benelli, G., Gozzo, M., & Toso, V. (2012). The social and economic burden of stroke survivors in Italy: A prospective, incidence-based, multi-centre cost of illness study. BMC Neurology, 12(1), 137. https://doi.org/10.1186/1471-2377-12-137

Feigin, V. L., Stark, B. A., Johnson, C. O., Roth, G. A., Bisignano, C., Abady, G. G., Abbasifard, M., Abbasi-Kangevari, M., Abd-Allah, F., Abedi, V., Abualhasan, A., Abu-Rmeileh, N. M., Abushouk, A. I., Adebayo, O. M., Agarwal, G., Agasthi, P., Ahinkorah, B. O., Ahmad, S., Ahmadi, S., … Murray, C. J. L. (2021). Global, regional, and national burden of stroke and its risk factors, 1990–2019: A systematic analysis for the Global Burden of Disease Study 2019. The Lancet Neurology, 20(10), 795–820. https://doi.org/10.1016/S1474-4422(21)00252-0

Ganapathy, V., Graham, G. D., DiBonaventura, M. D., Gillard, P. J., Goren, A., & Zorowitz, R. D. (2015). Caregiver burden, productivity loss, and indirect costs associated with caring for patients with poststroke spasticity. Clinical Interventions in Aging, 10, 1793–1802. https://doi.org/10.2147/CIA.S91123

Gillard, P., Ganapathy, V., Graham, G., Dibonaventura, M., Goren, A., & Zorowitz, R. (2015). Caregiver burden, productivity loss, and indirect costs associated with caring for patients with poststroke spasticity. Clinical Interventions in Aging, 10, 1793. https://doi.org/10.2147/CIA.S91123

Guo, Y., & Liu, Y. (2015). Family functioning and depression in primary caregivers of stroke patients in China. International Journal of Nursing Sciences, 2(2), 184–189. https://doi.org/10.1016/j.ijnss.2015.05.002

Hankey, G. J. (2017). The Role of Nutrition in the Risk and Burden of Stroke an Update of the Evidence. Stroke, 48(11), 3168–3174. https://doi.org/10.1161/STROKEAHA.117.016993

Huang, H., Zheng, T., Wang, S., Wei, L., Wang, Q., & Sun, Z. (2016). Serum 25-hydroxyvitamin D predicts early recurrent stroke in ischemic stroke patients. Nutrition, Metabolism, and Cardiovascular Diseases: NMCD, 26(10), 908–914. https://doi.org/10.1016/j.numecd.2016.06.009

Jungert, A., Spinneker, A., Nagel, A., & Neuhäuser-Berthold, M. (2014). Dietary intake and main food sources of vitamin D as a function of age, sex, vitamin D status, body composition, and income in an elderly German cohort. Food & Nutrition Research, 58, 10.3402/fnr.v58.23632. https://doi.org/10.3402/fnr.v58.23632

Keller, K., Geyer, M., Münzel, T., & Ostad, M. A. (2018). Gender-differences in prevalence and outcome of ischemic stroke and promoting factors of atrial thrombi. Artery Research, 22, 68–78. https://doi.org/10.1016/j.artres.2018.05.004

Kementerian Kesehatan RI. (2019). Laporan Riskesdas 2018 Nasional. Lembaga Penerbit Badan Penelitian dan Pengembangan Kesehatan Kementerian KesehatanRI. https://kesmas.kemkes.go.id/assets/upload/dir_519d41d8cd98f00/files/Hasil-riskesdas-2018_1274.pdf

Kessler, D., Egan, M., & Kubina, L.-A. (2014). Peer support for stroke survivors: A case study. BMC Health Services Research, 14, 256. https://doi.org/10.1186/1472-6963-14-256

Kotseva, K., Gerlier, L., Sidelnikov, E., Kutikova, L., Lamotte, M., Amarenco, P., & Annemans, L. (2019). Patient and caregiver productivity loss and indirect costs associated with cardiovascular events in Europe. European Journal of Preventive Cardiology, 26(11), 1150–1157. https://doi.org/10.1177/2047487319834770

Lekander, I., Willers, C., Euler, M. von, Lilja, M., Sunnerhagen, K. S., Pessah-Rasmussen, H., & Borgström, F. (2017). Relationship between functional disability and costs one and two years post stroke. PLOS ONE, 12(4), e0174861. https://doi.org/10.1371/journal.pone.0174861

Li, R.-C., Xu, W.-D., Lei, Y.-L., Bao, T., Yang, H.-W., Huang, W.-X., & Tang, H.-R. (2019). The risk of stroke and associated risk factors in a health examination population: A cross-sectional study. Medicine, 98(40), e17218. https://doi.org/10.1097/MD.0000000000017218

Lin, Q., Ye, T., Ye, P., Borghi, C., Cro, S., Damasceno, A., Khan, N., Nilsson, P. M., Prabhakaran, D., Ramirez, A., Schlaich, M. P., Schutte, A. E., Stergiou, G., Weber, M. A., Beaney, T., & Poulter, N. R. (2022). Hypertension in stroke survivors and associations with national premature stroke mortality: Data for 2·5 million participants from multinational screening campaigns. The Lancet Global Health, 10(8), e1141–e1149. https://doi.org/10.1016/S2214-109X(22)00238-8

Magwood, G. S., Nichols, M., Jenkins, C., Logan, A., Qunango, S., Zigbuo-Wenzler, E., & Ellis, C. (2020). Community-Based Interventions for Stroke Provided by Nurses and Community Health Workers: A Review of the Literature. The Journal of Neuroscience Nursing : Journal of the American Association of Neuroscience Nurses, 52(4), 152–159. https://doi.org/10.1097/JNN.0000000000000512

Mekonen, H. H., Birhanu, M. M., Mossie, T. B., & Gebreslassie, H. T. (2020). Factors associated with stroke among adult patients with hypertension in Ayder Comprehensive Specialized Hospital, Tigray, Ethiopia, 2018: A case-control study. PLoS ONE, 15(2), e0228650. https://doi.org/10.1371/journal.pone.0228650

Meschia, J. F., Bushnell, C., Boden-Albala, B., Braun, L. T., Bravata, D. M., Chaturvedi, S., Creager, M. A., Eckel, R. H., Elkind, M. S. V., Fornage, M., Goldstein, L. B., Greenberg, S. M., Horvath, S. E., Iadecola, C., Jauch, E. C., Moore, W. S., Wilson, J. A., American Heart Association Stroke Council, Council on Cardiovascular and Stroke Nursing, … Council on Hypertension. (2014). Guidelines for the primary prevention of stroke: A statement for healthcare professionals from the American Heart Association/American Stroke Association. Stroke, 45(12), 3754–3832. https://doi.org/10.1161/STR.0000000000000046

Milazzo, V., De Metrio, M., Cosentino, N., Marenzi, G., & Tremoli, E. (2017). Vitamin D and acute myocardial infarction. World Journal of Cardiology, 9(1), 14–20. https://doi.org/10.4330/wjc.v9.i1.14

Mondal, M. B. A., Hasan, A. T. M. H., Khan, N., & Mohammad, Q. D. (2022). Prevalence and risk factors of stroke in Bangladesh: A nationwide population-based survey. ENeurologicalSci, 28, 100414. https://doi.org/10.1016/j.ensci.2022.100414

Morris, R., & Morris, P. (2012). Participants’ experiences of hospital-based peer support groups for stroke patients and carers. Disability and Rehabilitation, 34(4), 347–354. https://doi.org/10.3109/09638288.2011.607215

Narasimhan, S., & Balasubramanian, P. (2017). Role of Vitamin D in the Outcome of Ischemic Stroke- A Randomized Controlled Trial. Journal of Clinical and Diagnostic Research : JCDR, 11(2), CC06-CC10. https://doi.org/10.7860/JCDR/2017/24299.9346

NHS. (2017, October 23). Vitamins and minerals. Nhs.Uk. https://www.nhs.uk/conditions/vitamins-and-minerals/

Nie, Z., Ji, X.-C., Wang, J., & Zhang, H.-X. (2017). Serum levels of 25-hydroxyvitamin D predicts infarct volume and mortality in ischemic stroke patients. Journal of Neuroimmunology, 313, 41–45. https://doi.org/10.1016/j.jneuroim.2017.10.002

Pan, B., Jin, X., Jun, L., Qiu, S., Zheng, Q., & Pan, M. (2019). The relationship between smoking and stroke: A meta-analysis. Medicine, 98(12), e14872. https://doi.org/10.1097/MD.0000000000014872

Park, K.-Y., Chung, P.-W., Kim, Y. B., Moon, H.-S., Suh, B.-C., Won, Y. S., Kim, J.-M., Youn, Y. C., & Kwon, O.-S. (2015). Serum Vitamin D Status as a Predictor of Prognosis in Patients with Acute Ischemic Stroke. Cerebrovascular Diseases (Basel, Switzerland), 40(1–2), 73–80. https://doi.org/10.1159/000434691

Pathak, A., Kumar, P., Pandit, A. K., Chakravarty, K., Misra, S., Yadav, A. K., & Prasad, K. (2018). Is Prevalence of Hypertension Increasing in First-Ever Stroke Patients?: A Hospital-Based Cross-Sectional Study. Annals of Neurosciences, 25(4), 219–222. https://doi.org/10.1159/000487066

Peters, S. A. E., Carcel, C., Millett, E. R. C., & Woodward, M. (2020). Sex differences in the association between major risk factors and the risk of stroke in the UK Biobank cohort study. Neurology, 95(20), e2715–e2726. https://doi.org/10.1212/WNL.0000000000010982

Peters, S. A. E., Huxley, R. R., & Woodward, M. (2013). Stroke, 44(9), 2394–2401. https://doi.org/10.1161/STROKEAHA.113.001624

Pusparini, P. (2018). Defisiensi Vitamin D Terhadap Penyakit (Vitamin D Deficiency and Diseases). Indonesian Journal of Clinical Pathology and Medical Laboratory, 21, 90. https://doi.org/10.24293/ijcpml.v21i1.1265

Rahayu, E. O. (2016). Perbedaan Risiko Stroke Berdasarkan Faktor Risiko Biologi pada Usia Produktif. Jurnal Berkala Epidemiologi, 4(September 2016), 113–125. https://doi.org/10.20473/jbe.v4i1.113-125

Ramos-Lima, M. J. M., Brasileiro, I. de C., de Lima, T. L., & Braga-Neto, P. (2018). Quality of life after stroke: Impact of clinical and sociodemographic factors. Clinics, 73, e418. https://doi.org/10.6061/clinics/2017/e418

Rao Ch., S., & Subash Y., E. (2013). The Effect of Chronic Tobacco Smoking and Chewing on the Lipid Profile. Journal of Clinical and Diagnostic Research : JCDR, 7(1), 31–34. https://doi.org/10.7860/JCDR/2012/5086.2663

Selim, F. O., Fahmi, R. M., Ali, A. E., Raafat, N., & Elsaid, A. F. (2019). Serum vitamin D levels in acute stroke patients. The Egyptian Journal of Neurology, Psychiatry and Neurosurgery, 55(1), 80. https://doi.org/10.1186/s41983-019-0129-0

Simbolon, P., Simbolon, N., & Ringo, M. S. (2018). Faktor Merokok dengan Kejadian Stroke di Rumah Sakit Santa Elisabeth Medan. Jurnal Kesehatan Manarang, 4(1), Article 1. https://doi.org/10.33490/jkm.v4i1.53

Sizar, O., Khare, S., Goyal, A., & Givler, A. (2022). Vitamin D Deficiency. In StatPearls. StatPearls Publishing. http://www.ncbi.nlm.nih.gov/books/NBK532266/

Sofyan, A. M., Sihombing, I. Y., & Hamra, Y. (2015). Hubungan Umur, Jenis Kelamin, dan Hipertensi dengan Kejadian Stroke. Medula (Jurnal Ilmiah Fakultas Kedokteran Universitas Halu Oleo), 1(1), Article 1. https://doi.org/10.46496/medula.v1i1.182

Spence, J. D. (2019). Nutrition and Risk of Stroke. Nutrients, 11(3), 647. https://doi.org/10.3390/nu11030647

Talebi, A., Amirabadizadeh, A., Nakhaee, S., Ahmadi, Z., & Mousavi-Mirzaei, S. M. (2020). Cerebrovascular disease: How serum phosphorus, vitamin D, and uric acid levels contribute to the ischemic stroke. BMC Neurology, 20(1), 116. https://doi.org/10.1186/s12883-020-01686-4

Tripkovic, L., Lambert, H., Hart, K., Smith, C. P., Bucca, G., Penson, S., Chope, G., Hyppönen, E., Berry, J., Vieth, R., & Lanham-New, S. (2012). Comparison of vitamin D2 and vitamin D3 supplementation in raising serum 25-hydroxyvitamin D status: A systematic review and meta-analysis. The American Journal of Clinical Nutrition, 95(6), 1357–1364. https://doi.org/10.3945/ajcn.111.031070

Turetsky, A., Goddeau, R. P., & Henninger, N. (2015). Low Serum Vitamin D Is Independently Associated with Larger Lesion Volumes after Ischemic Stroke. Journal of Stroke and Cerebrovascular Diseases: The Official Journal of National Stroke Association, 24(7), 1555–1563. https://doi.org/10.1016/j.jstrokecerebrovasdis.2015.03.051

Udani, G. (2013). Faktor Resiko Kejadian Stroke. Jurnal Kesehatan Metro Sai Wawai, VI(1), 49–57.

Vyas, M. V., Hackam, D. G., Silver, F. L., Laporte, A., & Kapral, M. K. (2016). Lost Productivity in Stroke Survivors: An Econometrics Analysis. Neuroepidemiology, 47(3–4), 164–170. https://doi.org/10.1159/000454730

Wacker, M., & Holick, M. F. (2013). Sunlight and Vitamin D. Dermato-Endocrinology, 5(1), 51–108. https://doi.org/10.4161/derm.24494

Wajda, J., Åšwiat, M., Owczarek, A. J., Brzozowska, A., Olszanecka-Glinianowicz, M., & Chudek, J. (2019). Severity of Vitamin D Deficiency Predicts Mortality in Ischemic Stroke Patients. Disease Markers, 2019, e3652894. https://doi.org/10.1155/2019/3652894

Wajngarten, M., & Silva, G. S. (2019). Hypertension and Stroke: Update on Treatment. European Cardiology Review, 14(2), 111–115. https://doi.org/10.15420/ecr.2019.11.1

Wang, Y., Dai, Y., Zheng, J., Xie, Y., Guo, R., Guo, X., Sun, G., Sun, Z., Sun, Y., & Zheng, L. (2019). Sex difference in the incidence of stroke and its corresponding influence factors: Results from a follow-up 8.4 years of rural China hypertensive prospective cohort study. Lipids in Health and Disease, 18(1), 72. https://doi.org/10.1186/s12944-019-1010-y

Wang, Y., Ji, H., Tong, Y., & Zhang, Z. (2014). Prognostic value of serum 25-hydroxyvitamin D in patients with stroke. Neurochemical Research, 39(7), 1332–1337. https://doi.org/10.1007/s11064-014-1316-0

WHO. (2020). Non communicable Diseases Progress Monitor 2020. World Health Organization. https://www.who.int/publications/i/item/9789240000490

WHO. (2022). Non communicable diseases. World Health Organization. https://www.who.int/news-room/fact-sheets/detail/noncommunicable-diseases

Williamson, J. D., Supiano, M. A., Applegate, W. B., Berlowitz, D. R., Campbell, R. C., Chertow, G. M., Fine, L. J., Haley, W. E., Hawfield, A. T., Ix, J. H., Kitzman, D. W., Kostis, J. B., Krousel-Wood, M. A., Launer, L. J., Oparil, S., Rodriguez, C. J., Roumie, C. L., Shorr, R. I., Sink, K. M., … SPRINT Research Group. (2016). Intensive vs Standard Blood Pressure Control and Cardiovascular Disease Outcomes in Adults Aged ≥75 Years: A Randomized Clinical Trial. JAMA, 315(24), 2673–2682. https://doi.org/10.1001/jama.2016.7050

Yarlagadda, K., Ma, N., & Doré, S. (2020). Vitamin D and Stroke: Effects on Incidence, Severity, and Outcome and the Potential Benefits of Supplementation. Frontiers in Neurology, 11, 384. https://doi.org/10.3389/fneur.2020.00384

Downloads

Published

2022-09-16

Issue

Section

Original Research Paper

SHARE THIS