Correlation Cholesterol and Triglyceride Level on Cognitive Function in Type 2 Diabetes Mellitus

Authors

  • Iin novita Nurhidayati Mahmuda Faculty Medicine, Universitas Muhammadiyah Surakarta, Kampus 4 Gonilan, Sukoharjo 57162, Indonesia
  • Fairuz Ulfah Faculty Medicine, Universitas Muhammadiyah Surakarta, Kampus 4 Gonilan, Sukoharjo 57162, Indonesia

DOI:

https://doi.org/10.31101/ijhst.v2i3.1913

Keywords:

cholesterol, triglycerides, cognitive function, diabetes mellitus type 2

Abstract

Diabetes Mellitus (DM) is a type of non-communicable disease that is still a public health problem both globally, regionally, nationally and locally. The prevalence of DM in the world is 1.9% and makes DM the seventh cause of death in the world. One of the complications caused by DM is a decrease in cognitive function. The triggers for cognitive function include high cholesterol and triglyceride levels. The purpose of this study was to determine the correlation between cholesterol and triglyceride leves on cognitive function in Type 2 Diabetes Mellitus at Boyolali. This study is an analytic observational study with a cross sectional approach .The subject are 51 respondents. The sampling technique used in this study was  purposive sampling technique. Data analyzed with chi-square test . it was found that there was a correlation between cholesterol level and cognitive function with a p-value of 0.003 <0.05 and there was also correlation triglyceride level and cognitive function with a p-value of 0.000 <0.05.  There is a significant correlation between cholesterol and triglyseride level with cognitive function in type II diabetic patient. 

Author Biographies

Iin novita Nurhidayati Mahmuda, Faculty Medicine, Universitas Muhammadiyah Surakarta, Kampus 4 Gonilan, Sukoharjo 57162

Internal Medicine Departement

Fairuz Ulfah, Faculty Medicine, Universitas Muhammadiyah Surakarta, Kampus 4 Gonilan, Sukoharjo 57162

Medical student

References

Bustan. (2015). Manajemen pengendalian penyakit tidak menular. Jakarta : Rineka Cipta.

Crichton, G.E., Sullivan, K.J., and Elias, M.F. 2016. Cholesterol and cognitive function in person free from stroke and dementia. In: Watson, R.R., and Meester, F.M., editors. Handbook of Cholesterol. 37-52.

Dahlan, Sopiyudin M. (2013). Besar Sampel dan Cara Pengambilan Sampel. Jakarta: Salemba Medika

Depkes RI. (2014). Waspada Diabetes Eat well live well. Situasi dan Analisis Diabetes. Jakarta:Infodatin

Dinas Kesehatan Kota Surakarta. (2017). Profil Kesehatan Kota Surakarta Tahun 2017. Surakarta : DKK Surakarta.

Ekawati, ER. (2012). Hubungan Kadar Glukosa Darah Terhadap Hypertriglycerida Pada Penderita Diabetes Mellitus. Prosiding Seminar Nasional Kimia Unesa 2012-ISBN:978-979-028-550 7

Ekoe, J. M., Zubin Punthakee MD, MSc, FRCPC, Thomas Ransom MD, MSc, FRCPC, Ally P. H.Prebtani BScPhm, MD, FRCPC, Ronald Goldenberg MD, FRCPC, FACE. (2013). Screening for Type 1 and Type 2, Canadian Journal of Diabetes, Volume 37 : S12-S15. Retrieved from www.canadianjournalofdiabetes.com.

Libby, P. (2012). The Pathogenesis, Prevention, and Treatment of Atherosclerosis. Dalam Longo, et al, penyunting. Harrison’s Principles of Internal Medicine 18th. Edisi ke-18. New York: The McGraw-Hill Companies. hlm. 1983-97

Martín, Mauricio G et al. (2014). Choles terol in brain disea se: somet imes determ inant and frequ ently impli cated. EMBO reports Vol 15 |No 10 | 2014

Sato, N. and Morishita, R. (2015). The roles of lipid and glucose metabolism in modulation of β-amyloid, tau, and neurodegeneration in the pathogenesis of Alzheimer disease. Aging Neuroscience.

Sufitria, Afriatin. (2016). Hubungan Hipertrigliseridemia Dengan Gangguan Kognitif Pada Pasien Stroke Di Unit Stroke RSUP dr. Sardjito. Skripsi. Fakultas Kedokteran UGM.

Suzuki, Ryo et al. (2010). Diabetes and Insulin Regulation Of Brain Cholesterol Metabolism. Cell Metab. 2010 December 1; 12(6): 567–579. doi:10.1016/j.cmet.2010.11.006.

Yin, Z., Shi, X., Kraus, V.B., Fitxgerald, S.M., Qian, H., Xu, J.W. (2012). High Normal Plasma Triglyserides are associated with preserved cognitive function in Chinese oldest old. Age and Ageing. 1-7.

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Published

2021-04-01

How to Cite

Mahmuda, I. novita N., & Ulfah, F. (2021). Correlation Cholesterol and Triglyceride Level on Cognitive Function in Type 2 Diabetes Mellitus. International Journal of Health Science and Technology, 2(3), 41–47. https://doi.org/10.31101/ijhst.v2i3.1913

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